Santo Domingo cruises

Find the perfect Santo Domingo cruise for your next trip!

Prices include all applicable taxes and port fees

80 Santo Domingo cruises

Prices include all applicable taxes and port fees

7 Night Caribbean And Antilles Cruise

Costa Favolosa
Costa Favolosa Recommended Cruise
Departing from:Fort-de-France, Martinique
Ports of call:Martinique Bay•Pointe-a-Pitre, Guadeloupe•Sea Of Antilles Darkest Spot•Port of Basseterre, St. Kitts, St. Kitts and Nevis•Road Town, Tortola, B.V.I.•Santo Domingo, Dominican Republic•Philipsburg, St. Maarten
Sailing dates:January 7•February 25, 2027

Bonus Offers:

  • Save $239 per person with this offer
Interior from $1,245 $1,006
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22 Night Ocean Cruises Cruise

Costa Favolosa
Costa Favolosa Recommended Cruise
Departing from:Hamburg, Germany
Ports of call:Ijmuiden, Netherlands•Dover (London), England•Le Havre (Paris), France•Lisbon, Portugal•Cadiz (Seville), Spain•Las Palmas, Gran Canaria, Canary Islands•Fort-de-France, Martinique•Pointe-a-Pitre, Guadeloupe•Sea Of Antilles Darkest Spot•Port of Basseterre, St. Kitts, St. Kitts and Nevis•Antigua, Antigua & Barbuda•Road Town, Tortola, B.V.I.
Sailing dates:November 8, 2026

Bonus Offers:

  • Save $483 per person with this offer
Interior from $2,547 $2,064
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7 Night Caribbean And Antilles Cruise

Costa Favolosa
Costa Favolosa Great Deal Recommended Cruise
Departing from:Santo Domingo, Dominican Republic
Ports of call:Antigua, Antigua & Barbuda•Martinique Bay•Fort-de-France, Martinique•Pointe-a-Pitre, Guadeloupe•Sea Of Antilles Darkest Spot•Port of Basseterre, St. Kitts, St. Kitts and Nevis•Philipsburg, St. Maarten
Sailing dates:January 18•February 1, 2027

Bonus Offers:

  • Save $159 per person with this offer
Interior from $838 $679
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28 Night Caribbean - Southern Cruise

Zuiderdam
Zuiderdam Recommended Cruise
Departing from:Miami, Florida
Ports of call:Nassau, Bahamas•Half Moon Cay (Little San Salvador Island), Bahamas•Ocho Rios, Jamaica•Santo Domingo, Dominican Republic•San Juan, Puerto Rico•Charlotte Amalie, St. Thomas, U.S. Virgin Islands•St. John's, Antigua•Castries, St. Lucia•Port of Spain, Trinidad•Willemstad, Curacao•Port of Oranjestad, Aruba, Caribbean•Santa Marta, Colombia
Sailing dates:October 30, 2027
Interior from $4,379/ pp
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7 Night Caribbean And Antilles Cruise

Costa Favolosa
Costa Favolosa Great Deal Recommended Cruise
Departing from:Santo Domingo, Dominican Republic
Ports of call:Philipsburg, St. Maarten•Martinique Bay•Fort-de-France, Martinique•Pointe-a-Pitre, Guadeloupe•Sea Of Antilles Darkest Spot•Port of Basseterre, St. Kitts, St. Kitts and Nevis•Road Town, Tortola, B.V.I.
Sailing dates:January 11, 2027

Bonus Offers:

  • Save $180 per person with this offer
Interior from $948 $768
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7 Night Caribbean And Antilles Cruise

Costa Favolosa
Costa Favolosa Great Deal Recommended Cruise
Departing from:Santo Domingo, Dominican Republic
Ports of call:Antigua, Antigua & Barbuda•Martinique Bay•Fort-de-France, Martinique•Pointe-a-Pitre, Guadeloupe•Sea Of Antilles Darkest Spot•Port of Basseterre, St. Kitts, St. Kitts and Nevis•Road Town, Tortola, B.V.I.
Sailing dates:January 4•February 15, 22, 2027

Bonus Offers:

  • Save $167 per person with this offer
Interior from $896 $729
View Itinerary

7 Night Caribbean And Antilles Cruise

Costa Favolosa
Costa Favolosa Great Deal Recommended Cruise
Departing from:Santo Domingo, Dominican Republic
Ports of call:Martinique Bay•Fort-de-France, Martinique•Pointe-a-Pitre, Guadeloupe•Sea Of Antilles Darkest Spot•Port of Basseterre, St. Kitts, St. Kitts and Nevis•Antigua, Antigua & Barbuda•Road Town, Tortola, B.V.I.
Sailing dates:December 7, 14, 2026

Bonus Offers:

  • Save $167 per person with this offer
Interior from $896 $729
View Itinerary

7 Night Caribbean And Antilles Cruise

Costa Favolosa
Costa Favolosa Great Deal Recommended Cruise
Departing from:Santo Domingo, Dominican Republic
Ports of call:Martinique Bay•Fort-de-France, Martinique•Pointe-a-Pitre, Guadeloupe•Philipsburg, St. Maarten•Sea Of Antilles Darkest Spot•Port of Basseterre, St. Kitts, St. Kitts and Nevis•Road Town, Tortola, B.V.I.
Sailing dates:December 21, 2026

Bonus Offers:

  • Save $207 per person with this offer
Interior from $1,085 $878
View Itinerary

23 Night Ocean Cruises Cruise

Costa Favolosa
Costa Favolosa Recommended Cruise
Departing from:Pointe-a-Pitre, Guadeloupe
Ports of call:Sea Of Antilles Darkest Spot•Port of Basseterre, St. Kitts, St. Kitts and Nevis•Road Town, Tortola, B.V.I.•Santo Domingo, Dominican Republic•Philipsburg, St. Maarten•Martinique Bay•Fort-de-France, Martinique•Antigua, Antigua & Barbuda•Santa Cruz de Tenerife, Canary Islands•Tangier, Morocco•Malaga, Spain•Barcelona, Spain
Sailing dates:February 26, 2027

Bonus Offers:

  • Save $485 per person with this offer
Interior from $2,525 $2,040
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25 Night Ocean Cruises Cruise

Costa Favolosa
Costa Favolosa Recommended Cruise
Departing from:Hamburg, Germany
Ports of call:Ijmuiden, Netherlands•Dover (London), England•Le Havre (Paris), France•Lisbon, Portugal•Cadiz (Seville), Spain•Las Palmas, Gran Canaria, Canary Islands•Fort-de-France, Martinique•Pointe-a-Pitre, Guadeloupe•Sea Of Antilles Darkest Spot•Port of Basseterre, St. Kitts, St. Kitts and Nevis•Antigua, Antigua & Barbuda•Road Town, Tortola, B.V.I.
Sailing dates:November 8, 2026

Bonus Offers:

  • Save $503 per person with this offer
Interior from $2,656 $2,153
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Showing Results 10 of 80

About Santo Domingo cruises

Cruises to or from Santo Domingo sail mostly to the Caribbean and Europe. Costa runs most of the sailings here. Trips include 7- to 21-night itineraries with stops at Pointe-a-Pitre, Fort-de-France, and Port of Basseterre.

Sailings to or from Santo Domingo run from November 2026 to March 2029, most often in December. Choose from interior, oceanview, balcony, and suite cabins. You can sail on Costa Serena and Costa Favolosa. Take a look at the departure dates and itineraries above to find a sailing that fits your plans.

Frequently asked questions

Which ports do Santo Domingo cruises visit?

Santo Domingo itineraries include stops at Port of Basseterre, Fort-de-France, and Road Town. 104 sailings stop at Port of Basseterre.

Which cruise lines sail to or from Santo Domingo?

Costa sails to or from Santo Domingo.

Where do Santo Domingo cruises leave from?

You can sail from Pointe-a-Pitre, Santo Domingo, and Fort-de-France. Departures are most frequent from Pointe-a-Pitre.

Which ships sail to or from Santo Domingo most often?

Ships sailing most often include Costa Serena and Costa Favolosa.

What kinds of cabins are available?

You can choose interior, oceanview, balcony, and suite cabins.

How many cruises and ships are sailing to or from Santo Domingo?

There are currently 118 sailings on 6 ships. Departures run from November 2026 to March 2029.

What are the shortest and longest Santo Domingo cruises?

The shortest trip is 4 nights, and the longest is 28 nights. Most trips last 7 to 21 nights.

How long are Santo Domingo cruises?

Trips include 7- to 21-night itineraries.